Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Azelaic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL15378185 | 0.98 | BBOX1 (0.48) | BBOX1MEN1LMNAKMT2ACYP3A4 | |
| Glutarate SCHEMBL17982129 | 0.93 | MEN1 (0.52) | BBOX1MEN1LMNAKMT2ACYP3A4 | |
| Nonanoate SCHEMBL29370695 | 0.92 | FABP3 (0.55) | BBOX1CA1FABP3 | |
| Octanoic Acid SCHEMBL2761867 | 0.92 | FABP3 (0.55) | BBOX1CA1FABP3 | |
| Stearic Acid SCHEMBL840883 | 0.92 | FABP3 (0.55) | BBOX1CA1FABP3 | |
| Myristic Acid SCHEMBL8588822 | 0.92 | FABP3 (0.55) | BBOX1CA1FABP3 | |
| Dodecanoate SCHEMBL19253062 | 0.92 | FABP3 (0.55) | BBOX1CA1FABP3 | |
| Decanoic Acid SCHEMBL580470 | 0.92 | FABP3 (0.55) | BBOX1CA1FABP3 | |
| Palmitic Acid SCHEMBL10396224 | 0.92 | FABP3 (0.55) | BBOX1CA1FABP3 | |
| Stearic Acid SCHEMBL3459529 | 0.91 | FABP3 (0.53) | BBOX1CA1FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116637037-A | Preparation method and application of siRNA supermolecule microcapsule with whitening effect | 丁妈给力(北京)生物科技有限公司 | 2023-08-25 | — | — | CN | claimed |
| US-20250186319-A1 | ANAPLEROTIC COMPOSITIONS AND USES THEREOF | EXCELLA BIOSCIENTIFIC LTD (IL) | 2025-06-12 | — | — | US | disclosed |
| CN-116637037-A | Preparation method and application of siRNA supermolecule microcapsule with whitening effect | 丁妈给力(北京)生物科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-116059129-A | Skin moisturizer and preparation method thereof | 广东丸美生物技术股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| US-6120779-A | MOISTURIZING | SOMA TECHNOLOGIES (US) | 2000-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250186319-A1 | ANAPLEROTIC COMPOSITIONS AND USES THEREOF | OAT, PC, ACAT1 | BBOX1 1144/4885MEN1 2688/4885LMNA 2416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.