Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084665 | 0.79 | CYP1A2 (0.57) | CYP1A2MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8076747 | 0.74 | CYP1A2 (0.55) | CYP1A2MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8089979 | 0.71 | CYP1A2 (0.51) | CYP1A2MAPTKMT2AALDH1A1POLB | |
| SCHEMBL8076711 | 0.70 | MAPT (0.51) | CYP1A2MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8084078 | 0.70 | CYP1A2 (0.58) | CYP1A2MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8084786 | 0.70 | GCGR (0.59) | CYP1A2MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8089902 | 0.69 | ALDH1A1 (0.50) | CYP1A2MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8084836 | 0.69 | ALDH1A1 (0.54) | CYP1A2MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8084106 | 0.69 | NPC1 (0.50) | CYP1A2MAPTKMT2AALDH1A1POLB | |
| SCHEMBL8084757 | 0.68 | ALDH1A1 (0.49) | CYP1A2MAPTKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |