Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320455 | 0.75 | FKBP1A (0.61) | GSK3BMAPTHPGDAKR1C3L3MBTL1 | |
| SCHEMBL5063533 | 0.75 | GSK3B (0.73) | GSK3BMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL7345341 | 0.75 | PLOD2 (0.56) | GSK3BMAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL8081315 | 0.74 | GSK3B (0.45) | GSK3BMAPTAKR1C3L3MBTL1ALDH1A1 | |
| SCHEMBL7025664 | 0.73 | GSK3B (0.71) | GSK3BMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL13606920 | 0.73 | NPC1 (0.49) | GSK3BMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL11390443 | 0.73 | MLYCD (0.60) | GSK3BMAPTHPGDAKR1C3L3MBTL1 | |
| SCHEMBL50003 | 0.73 | GSK3B (0.71) | GSK3BMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL541208 | 0.73 | GSK3B (1.00) | GSK3BMAPTHPGDAKR1C3L3MBTL1 | |
| SCHEMBL4342386 | 0.73 | ALDH1A1 (0.49) | GSK3BMAPTHPGDL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |