Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27608865 | 0.88 | FAAH (0.53) | FKBP1AMAPTHPGDGSK3BMAPK1 | |
| SCHEMBL6320418 | 0.87 | ALDH1A1 (0.62) | MAPTHPGDGSK3BMAPK1LMNA | |
| SCHEMBL6327817 | 0.81 | LMNA (0.73) | MAPTMAPK1L3MBTL1LMNACASP3 | |
| SCHEMBL27608870 | 0.80 | ALDH1A1 (0.57) | FKBP1AMAPTHPGDL3MBTL1GAA | |
| SCHEMBL6320250 | 0.75 | MAPT (0.58) | FKBP1AMAPTHPGDGSK3BLMNA | |
| SCHEMBL8088532 | 0.75 | GSK3B (0.57) | MAPTHPGDGSK3BMAPK1L3MBTL1 | |
| SCHEMBL18867933 | 0.74 | AKR1C3 (0.65) | MAPTHPGDMAPK1LMNASMN1; SMN2 | |
| SCHEMBL4972149 | 0.74 | AKR1C3 (0.65) | MAPTHPGDMAPK1LMNASMN1; SMN2 | |
| SCHEMBL11847871 | 0.74 | LMNA (0.64) | MAPTHPGDMAPK1L3MBTL1LMNA | |
| SCHEMBL6318784 | 0.74 | MAPT (0.64) | MAPTGSK3BMAPK1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |