Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077770 | 0.86 | LMNA (0.39) | MAPTCA2TAAR1TP53NISCH | |
| SCHEMBL6493292 | 0.84 | CNR1 (0.40) | NPC1RAB9AMAPTGFERCA2 | |
| SCHEMBL7154087 | 0.81 | NPC1 (0.37) | NPC1RAB9AMAPTGFERCA2 | |
| SCHEMBL8089864 | 0.81 | MAOB (0.41) | NPC1RAB9AMAPTGFERTAAR1 | |
| SCHEMBL5797082 | 0.78 | MAOB (0.35) | NPC1RAB9AMAPTALOX5MAOB | |
| SCHEMBL2724725 | 0.78 | NPC1 (0.35) | NPC1RAB9AMAPTGFERCA2 | |
| SCHEMBL9648734 | 0.77 | ACHE (0.41) | NPC1RAB9AMAPTSMN1; SMN2MAOB | |
| SCHEMBL10435172 | 0.75 | MCL1 (0.46) | NPC1RAB9AMAPTGFERCA2 | |
| SCHEMBL8169371 | 0.74 | PLAU (0.38) | NPC1RAB9AMAPTGFERMCL1 | |
| SCHEMBL8093170 | 0.74 | NPBWR1 (0.49) | ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051394-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037607-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1999-07-29 | — | — | WO | disclosed |