Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 11/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093681 | 0.84 | NOTUM (0.45) | SLC5A1HCRTR1HCRTR2DRD2DRD3 | |
| SCHEMBL8666480 | 0.82 | DRD2 (0.37) | GRM2SLC5A1HCRTR1HCRTR2DRD2 | |
| SCHEMBL5827283 | 0.81 | MEN1 (0.46) | DRD2DRD3 | |
| SCHEMBL8096256 | 0.79 | ROCK2 (0.39) | GRIN1GRIN2BHCRTR1HCRTR2EPHX2 | |
| SCHEMBL8666490 | 0.77 | KMT2A (0.35) | HCRTR1DRD2DRD3 | |
| SCHEMBL8668048 | 0.73 | HCRTR1 (0.42) | GRM2GRIN1GRIN2AGRIN2BSLC5A1 | |
| SCHEMBL17893797 | 0.69 | GRIN1 (0.45) | GRM2GRIN1GRIN2AGRIN2BHCRTR1 | |
| SCHEMBL8556168 | 0.68 | DRD2 (0.44) | HCRTR1HCRTR2DRD2DRD3MCHR1 | |
| SCHEMBL8099428 | 0.68 | CA12 (0.46) | DRD2DRD3 | |
| SCHEMBL8556361 | 0.68 | DRD2 (0.44) | HCRTR1HCRTR2DRD2DRD3MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705456-A | AZETIDIN-2-ONES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |