Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FADS1 | O60427 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096256 | 0.90 | ROCK2 (0.39) | KMT2AROCK2HCRTR1TOP2A | |
| SCHEMBL8093681 | 0.80 | NOTUM (0.45) | ROCK2HCRTR1TOP2ADRD2DRD3 | |
| SCHEMBL8666484 | 0.77 | GRM2 (0.41) | HCRTR1DRD2DRD3 | |
| SCHEMBL8666480 | 0.76 | DRD2 (0.37) | KMT2AFADS1HCRTR1DRD2DRD3 | |
| SCHEMBL5827283 | 0.74 | MEN1 (0.46) | KMT2AALDH1A1POLBMAPTMEN1 | |
| SCHEMBL8670349 | 0.73 | KMT2A (0.33) | KMT2AALDH1A1FADS1ROCK2MAPT | |
| SCHEMBL6508236 | 0.72 | ROCK2 (0.38) | KMT2AALDH1A1ROCK2HCRTR1TOP2A | |
| SCHEMBL8089006 | 0.68 | TSHR (0.36) | — | |
| SCHEMBL8082052 | 0.67 | SLC6A2 (0.45) | KMT2AMAPTMEN1 | |
| SCHEMBL8090197 | 0.66 | ALDH1A1 (0.35) | KMT2AALDH1A1MAPTMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705456-A | AZETIDIN-2-ONES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |