Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5882272 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TSHRFDPSMAPTAOX1 | |
| SCHEMBL14016964 | 0.79 | CYP1A2 (0.52) | MAPTL3MBTL1NPSR1GAAHTT | |
| SCHEMBL27002034 | 0.78 | MAPT (0.53) | CNR2ALDH1A1TSHRMAPTL3MBTL1 | |
| SCHEMBL27002045 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TSHRFDPSMAPTHPGD | |
| SCHEMBL1965979 | 0.75 | ALDH1A1 (0.63) | ALDH1A1TSHRFDPSMAPTAOX1 | |
| SCHEMBL6963840 | 0.75 | FDPS (0.79) | ALDH1A1TSHRFDPSMAPTHPGD | |
| SCHEMBL7344641 | 0.75 | ALDH1A1 (0.54) | ALDH1A1TSHRFDPSAOX1HPGD | |
| SCHEMBL5111350 | 0.75 | FDPS (0.69) | CNR2ALDH1A1TSHRFDPSMAPT | |
| SCHEMBL21738286 | 0.74 | TTR (0.51) | ALDH1A1TSHRFDPSMAPTAOX1 | |
| SCHEMBL8310250 | 0.74 | FDPS (0.77) | ALDH1A1TSHRFDPSMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |