Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081324 | 0.80 | NR4A2 (0.57) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7345341 | 0.79 | PLOD2 (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13606920 | 0.78 | NPC1 (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL4342386 | 0.77 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7334312 | 0.74 | PDE4A (0.42) | GRM4RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL1432939 | 0.72 | MAOB (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8095122 | 0.72 | NPC1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL27931867 | 0.71 | RAB9A (0.57) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9248136 | 0.70 | NPC1 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8088532 | 0.69 | GSK3B (0.57) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |