Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097654 | 0.84 | ALOX15 (0.43) | TSHRALDH1A1HSD17B10MAPTALOX15 | |
| SCHEMBL8105245 | 0.83 | ALDH1A1 (0.47) | TSHRDRD2DRD3ALDH1A1MAPT | |
| SCHEMBL10729227 | 0.80 | TSHR (0.36) | TSHRDRD2DRD3ALDH1A1HSD17B10 | |
| SCHEMBL8090023 | 0.80 | ALDH1A1 (0.33) | TSHRDRD2DRD3ALDH1A1HSD17B10 | |
| SCHEMBL10733179 | 0.80 | SLC6A2 (0.46) | MAPTMEN1ALOX12KMT2A | |
| SCHEMBL8090604 | 0.79 | KAT2B (0.49) | DRD2DRD3ALDH1A1HSD17B10MAPT | |
| SCHEMBL8098966 | 0.78 | ADRB1 (0.36) | ADRB1 | |
| SCHEMBL8103224 | 0.78 | MEN1 (0.44) | TSHRALDH1A1MAPTALOX15MEN1 | |
| SCHEMBL8099397 | 0.75 | MAPT (0.59) | ALDH1A1MAPTMEN1KMT2ANOTUM | |
| SCHEMBL8097791 | 0.74 | L3MBTL1 (0.45) | DRD2DRD3ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |
| US-4664694-A | NONPHYTOTOXIC | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0200415-A1 | Substituted thiazolidinones | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |