Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | PMM2 | O15305 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089589 | 0.83 | MAPT (0.54) | MAPTNOTUMAADATADRA1BPMM2 | |
| SCHEMBL8097784 | 0.81 | MGLL (0.41) | MAPTNOTUMAADATALDH1A1HSD11B1 | |
| SCHEMBL8097654 | 0.77 | ALOX15 (0.43) | MAPTALDH1A1HTT | |
| SCHEMBL10733179 | 0.76 | SLC6A2 (0.46) | MAPTKMT2AMEN1HTR1A | |
| SCHEMBL8105245 | 0.76 | ALDH1A1 (0.47) | MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8089631 | 0.75 | P2RX7 (0.42) | NOTUMAADATPHOSPHO1ALDH1A1HTR1A | |
| SCHEMBL8097250 | 0.74 | MAPT (1.00) | MAPTNOTUMADRA1BPMM2MPI | |
| SCHEMBL8090604 | 0.73 | KAT2B (0.49) | MAPTPHOSPHO1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8098695 | 0.70 | MAPT (0.41) | MAPTNOTUMALDH1A1MCOLN3KMT2A | |
| SCHEMBL8103236 | 0.70 | NOTUM (0.43) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |