Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096821 | 0.84 | HPN (0.48) | HPNMEN1KMT2AMAPTSCN2A | |
| SCHEMBL8105245 | 0.80 | ALDH1A1 (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8096938 | 0.77 | FADS1 (0.44) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8089618 | 0.77 | FAAH (0.42) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL8097791 | 0.77 | L3MBTL1 (0.45) | KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL8090453 | 0.77 | ATM (0.48) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8090329 | 0.76 | HPN (0.51) | HPNMEN1KMT2AMAPTSCN2A | |
| SCHEMBL8103224 | 0.76 | MEN1 (0.44) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL8097196 | 0.75 | MGLL (0.45) | KMT2AMAPTALDH1A1 | |
| SCHEMBL8103621 | 0.74 | NSD2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |