Hydrochloric Acid

Hydrochloric Acid

SCHEMBL20337306

CC(C)c1ccccc1/N=C/c1cccc(/C=N/c2ccccc2C(C)C)n1.[Cl-].[Cl-].[Fe+2]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 1/20 0.33
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SIGMAR1 Q99720 3/20 0.36
NR4A1 P22736 1/20 0.35
NOS3 P29474 2/20 0.35
NOS1 P29475 2/20 0.35
NOS2 P35228 2/20 0.35
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28685917 1.00 ALDH1A1 (0.38) ALDH1A1MAPTPLA2G1BATG4BHPGD
SCHEMBL5587992 0.97 MAPT (0.40) ALDH1A1MAPTPLA2G1BATG4BHPGD
SCHEMBL8089705 0.97 MAPT (0.40) ALDH1A1MAPTPLA2G1BATG4BHPGD
SCHEMBL20337312 0.95 MAPT (0.39) ALDH1A1MAPTPLA2G1BATG4BHPGD
SCHEMBL5587603 0.95 MAPT (0.39) ALDH1A1MAPTPLA2G1BATG4BHPGD
SCHEMBL20337311 0.95 MAPT (0.39) ALDH1A1MAPTPLA2G1BATG4BHPGD
SCHEMBL20337307 0.91 MAPT (0.37) ALDH1A1MAPTPLA2G1BATG4BHPGD
Acetone SCHEMBL28791784 0.88 ALDH1A1 (0.39) ALDH1A1MAPTPLA2G1BATG4BHPGD
Acetone SCHEMBL28791786 0.88 ALDH1A1 (0.39) ALDH1A1MAPTPLA2G1BATG4BHPGD
SCHEMBL27993966 0.84 NR4A1 (0.54) ALDH1A1HPGDKDM4EHSD17B10NR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562799-B1 ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL CO LP (US) 2023-08-23 EP disclosed
US-11358914-B2 Ethylene oligomerization processes CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2022-06-14 US disclosed
US-20210214289-A1 Ethylene Oligomerization Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2021-07-15 US disclosed
US-10793489-B2 Ethylene oligomerization processes CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2020-10-06 US disclosed
US-10604457-B2 Ethylene oligomerization processes CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2020-03-31 US disclosed
US-20200095178-A1 Ethylene Oligomerization Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2020-03-26 US disclosed
US-10544070-B2 Ethylene oligomerization process CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2020-01-28 US disclosed
EP-3562800-A1 ETHYLENE OLIGOMERIZATION PROCESSES Chevron Phillips Chemical Company LP (US) 2019-11-06 EP disclosed
EP-3562799-A1 ETHYLENE OLIGOMERIZATION PROCESSES Chevron Phillips Chemical Company LP (US) 2019-11-06 EP disclosed
US-20190276377-A1 Ethylene Oligomerization Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2019-09-12 US disclosed
US-20190194089-A1 Ethylene Oligomerization Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2019-06-27 US disclosed
WO-2018128861-A1 ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-07-12 WO disclosed
US-20180186708-A1 Ethylene Oligomerization Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2018-07-05 US disclosed
US-20180186709-A1 Ethylene Oligomerizaton Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2018-07-05 US disclosed
WO-2018125826-A1 ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180186708-A1 Ethylene Oligomerization Processes MAX, AP1M1, AP2M1 SLC6A2 3311/4885ALDH1A1 4669/4885MAPT 922/4885
US-20190276377-A1 Ethylene Oligomerization Processes NOD2, AP1M1, AP2M1 SLC6A2 3907/4885ALDH1A1 4471/4885MAPT 2760/4885
US-20190194089-A1 Ethylene Oligomerization Processes NOD2, AP1M1, AP2M1 SLC6A2 3907/4885ALDH1A1 4471/4885MAPT 2760/4885
US-10793489-B2 Ethylene oligomerization processes NOD2, AP1M1, AP2M1 SLC6A2 3907/4885ALDH1A1 4471/4885MAPT 2760/4885
US-10544070-B2 Ethylene oligomerization process NOD2, AP1M1, AP2M1 SLC6A2 3944/4885ALDH1A1 4457/4885MAPT 2823/4885
US-10604457-B2 Ethylene oligomerization processes EPS15, PICALM, AP2M1 SLC6A2 4467/4885ALDH1A1 4824/4885MAPT 1342/4885
US-20200095178-A1 Ethylene Oligomerization Processes NOD2, AP1M1, AP2M1 SLC6A2 3907/4885ALDH1A1 4471/4885MAPT 2760/4885
US-20180186709-A1 Ethylene Oligomerizaton Processes PICALM, EPS15, EPN1 SLC6A2 4185/4885ALDH1A1 4825/4885MAPT 1506/4885
US-20210214289-A1 Ethylene Oligomerization Processes MAX, AP1M1, AP2M1 SLC6A2 3311/4885ALDH1A1 4669/4885MAPT 922/4885
US-11358914-B2 Ethylene oligomerization processes MAX, AP1M1, AP2M1 SLC6A2 3311/4885ALDH1A1 4669/4885MAPT 922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.