Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8082052 | 0.88 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HDAC1HDAC8 | |
| SCHEMBL8089006 | 0.82 | TSHR (0.36) | L3MBTL1MCHR1 | |
| SCHEMBL7819041 | 0.81 | CYP1A2 (0.44) | RAD51L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL8089969 | 0.78 | NOTUM (0.38) | RAD51NOTUMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8090197 | 0.78 | ALDH1A1 (0.35) | NOTUMMEN1KMT2AMAPT | |
| SCHEMBL8089008 | 0.76 | IDO1 (0.33) | — | |
| SCHEMBL8096227 | 0.71 | RAD51 (0.38) | RAD51NOTUMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5827283 | 0.69 | MEN1 (0.46) | NOTUML3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL8082058 | 0.67 | MAPT (0.59) | RAD51NOTUMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8666490 | 0.65 | KMT2A (0.35) | MEN1KMT2ALMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022976-A | Process for the production of 5-hydroxyoxazolidinones | ZENECA LIMITED | 2000-02-08 | — | — | US | disclosed |
| EP-0880510-A1 | PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES | ZENECA LIMITED (GB) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028138-A1 | PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES | ZENECA LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |