Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.33 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.33 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.33 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.33 |
| ▸ | NPPA | P01160 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090127 | 0.93 | KDM4E (0.36) | KDM4EF13A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8095467 | 0.92 | CYP3A4 (0.38) | KDM4ENPC1CYP1A2CYP2C19RAB9A | |
| SCHEMBL8095269 | 0.89 | MMP1 (0.38) | CA1CA2CYP2C19 | |
| SCHEMBL8095286 | 0.89 | NPY4R (0.38) | KDM4EF13A1MME | |
| SCHEMBL8098091 | 0.87 | MMP8 (0.43) | MMENPC1CYP2D6CYP2C19 | |
| SCHEMBL8083627 | 0.85 | SMN1; SMN2 (0.44) | CA1CA2MAPTSMN1; SMN2 | |
| SCHEMBL8095466 | 0.85 | CYP2C19 (0.39) | KDM4ENPC1CYP1A2CYP2C19RAB9A | |
| SCHEMBL8090160 | 0.84 | MTNR1A (0.41) | CA1CA2RAB9A | |
| SCHEMBL8090113 | 0.82 | CYP2C19 (0.38) | KDM4EPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8095266 | 0.82 | MMP1 (0.39) | KDM4ECA1CA2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |