Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.38 |
| ▸ | NPY1R | P25929 | 9/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.36 |
| ▸ | NPY2R | P49146 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095279 | 0.94 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2RKDM4E | |
| SCHEMBL8090189 | 0.93 | MMP8 (0.37) | KDM4EMME | |
| SCHEMBL8095221 | 0.89 | MMP8 (0.41) | MME | |
| SCHEMBL8090134 | 0.89 | KDM4E (0.36) | KDM4EF13A1MME | |
| SCHEMBL8098074 | 0.86 | EPHX1 (0.35) | — | |
| SCHEMBL8090174 | 0.86 | F2 (0.39) | KDM4ETAAR1MME | |
| SCHEMBL8091593 | 0.85 | MTNR1A (0.41) | — | |
| SCHEMBL8095158 | 0.84 | MMP8 (0.36) | — | |
| SCHEMBL8091531 | 0.84 | MMP8 (0.35) | — | |
| SCHEMBL8090095 | 0.83 | KDM4E (0.44) | KDM4EF13A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |