Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098268 | 0.85 | SMN1; SMN2 (0.35) | HDAC1HDAC3HDAC2HDAC8MAPT | |
| SCHEMBL8090679 | 0.85 | MAPT (0.43) | MEN1MAPTKMT2AHTR1AADRA1D | |
| SCHEMBL8083652 | 0.81 | PPARG (0.36) | S1PR1S1PR4S1PR3S1PR5MRGPRX4 | |
| SCHEMBL8098486 | 0.80 | AR (0.35) | S1PR1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL8098731 | 0.80 | CYP1A2 (0.34) | MEN1KMT2A | |
| SCHEMBL8083938 | 0.79 | RHOC (0.35) | HDAC1MEN1MAPTKMT2A | |
| SCHEMBL8604509 | 0.78 | L3MBTL1 (0.41) | MAPT | |
| SCHEMBL8098784 | 0.78 | NPSR1 (0.39) | MEN1MAPTKMT2A | |
| SCHEMBL8602899 | 0.76 | ALDH1A1 (0.39) | S1PR1S1PR4S1PR3S1PR5HDAC1 | |
| SCHEMBL8090772 | 0.74 | PTGER4 (0.41) | HDAC1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |