SCHEMBL8090780

SCHEMBL8090780

CCOC1CCC(CC(=O)Cc2c(C)cc(C)cc2C)(CC(=O)OC)CC1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 4/20 0.32
NLRP3 Q96P20 1/20 0.32
P2RX7 Q99572 1/20 0.32
CHRM2 P08172 2/20 0.32
CHRM4 P08173 2/20 0.32
CHRM5 P08912 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
APP P05067 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089426 0.91 DPP4 (0.32) P2RX7
SCHEMBL8096827 0.88 THRB (0.32) P2RX7
SCHEMBL8089299 0.87 P2RX7 (0.32) NLRP3P2RX7
SCHEMBL8082691 0.87 CHRM2 (0.35) MMP1NLRP3P2RX7CHRM2CHRM4
SCHEMBL8094213 0.86 KMT2A (0.38)
SCHEMBL8089218 0.85 KMT2A (0.37)
SCHEMBL8089298 0.85 KMT2A (0.37)
SCHEMBL8090997 0.84 P2RX3 (0.32)
SCHEMBL8090778 0.81 TAS1R3 (0.32)
Bicarbonate SCHEMBL8848396 0.81 CHRM2 (0.34) MMP1P2RX7CHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6150304-A HERBICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-11-21 US disclosed
US-5840661-A HERBICIDES OR INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-11-24 US disclosed