Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090780 | 0.91 | MMP1 (0.32) | P2RX7 | |
| SCHEMBL8096827 | 0.90 | THRB (0.32) | EPHX2P2RX7MAPTTP53KMT2A | |
| SCHEMBL8094213 | 0.89 | KMT2A (0.38) | EPHX2MAPTTP53KMT2A | |
| SCHEMBL8089298 | 0.87 | KMT2A (0.37) | EPHX2MAPTTP53KMT2A | |
| SCHEMBL8089218 | 0.87 | KMT2A (0.37) | EPHX2MAPTTP53KMT2A | |
| SCHEMBL8089299 | 0.87 | P2RX7 (0.32) | EPHX2P2RX7 | |
| SCHEMBL8090997 | 0.86 | P2RX3 (0.32) | MAPT | |
| SCHEMBL8096961 | 0.85 | L3MBTL1 (0.35) | P2RX7MAPTKMT2A | |
| SCHEMBL8090778 | 0.83 | TAS1R3 (0.32) | — | |
| Bicarbonate SCHEMBL8848378 | 0.81 | DPP4 (0.33) | DPP4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150304-A | HERBICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-21 | — | — | US | disclosed |
| US-5840661-A | HERBICIDES OR INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |