Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 11/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084547 | 0.80 | ALDH1A1 (0.36) | MALT1CASP3 | |
| SCHEMBL7267575 | 0.80 | ABCC9 (0.37) | ABCC9MALT1NSD2ABCB1CASP3 | |
| SCHEMBL8088432 | 0.79 | PDE4A (0.43) | ABCC9MALT1NSD2ABCB1CASP3 | |
| SCHEMBL9371935 | 0.78 | ABCC9 (0.38) | ABCC9MALT1NSD2ABCB1CASP3 | |
| SCHEMBL8077233 | 0.78 | ABCC9 (0.40) | ABCC9MALT1ABCB1CASP3 | |
| SCHEMBL8085116 | 0.78 | ABCC9 (0.35) | ABCC9MALT1NSD2PGRABCB1 | |
| SCHEMBL8090488 | 0.77 | ABCC9 (0.36) | ABCC9MALT1NSD2ABCB1CASP3 | |
| SCHEMBL8076916 | 0.75 | ABCC9 (0.38) | ABCC9MALT1ABCB1 | |
| SCHEMBL8085086 | 0.75 | MALT1 (0.35) | ABCC9MALT1ABCB1CASP3 | |
| SCHEMBL8090648 | 0.74 | ABCC9 (0.35) | ABCC9MALT1ABCB1TDP2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5387587-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| US-5013853-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-05-07 | — | — | US | disclosed |