Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085006 | 0.80 | ADRA2A (0.43) | CYP19A1CYP11B1CYP11B2NISCHADRA2A | |
| SCHEMBL8091875 | 0.80 | ADRA2A (0.43) | CYP19A1CYP11B1CYP11B2NISCHADRA2A | |
| SCHEMBL8092401 | 0.80 | ADRA2A (0.43) | CYP19A1CYP11B1CYP11B2NISCHADRA2A | |
| SCHEMBL8097775 | 0.74 | ACHE (0.38) | ADRA2A | |
| Fumaric Acid SCHEMBL8091361 | 0.69 | KDM1A (0.42) | KDM1ACYP19A1CYP11B1CYP11B2NISCH | |
| Fumaric Acid SCHEMBL27554094 | 0.69 | KDM1A (0.42) | KDM1ACYP19A1CYP11B1CYP11B2NISCH | |
| Fumaric Acid SCHEMBL8091353 | 0.69 | KDM1A (0.42) | KDM1ACYP19A1CYP11B1CYP11B2NISCH | |
| SCHEMBL8097409 | 0.69 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL8097280 | 0.68 | ADRA2A (0.50) | ADRA2A | |
| SCHEMBL8084346 | 0.66 | ADRA2A (0.34) | CYP19A1CYP11B1CYP11B2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |