Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 6/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092912 | 0.86 | SLC6A4 (0.35) | CYP19A1HTR1AMCHR1 | |
| SCHEMBL8085006 | 0.76 | ADRA2A (0.43) | CYP19A1HTR1A | |
| SCHEMBL8091875 | 0.76 | ADRA2A (0.43) | CYP19A1HTR1A | |
| SCHEMBL8091868 | 0.74 | CYP19A1 (0.37) | CYP19A1PREPHTR1AHTR1DGBA1 | |
| Fumaric Acid SCHEMBL8097408 | 0.71 | CYP19A1 (0.38) | CYP19A1PREPHTR1AGBA1MTNR1A | |
| Fumaric Acid SCHEMBL8097411 | 0.71 | CYP19A1 (0.38) | CYP19A1PREPHTR1AGBA1MTNR1A | |
| SCHEMBL8084693 | 0.70 | SLC6A2 (0.36) | — | |
| SCHEMBL8091356 | 0.69 | KDM1A (0.40) | CYP19A1 | |
| SCHEMBL6950361 | 0.67 | CYP19A1 (0.46) | CYP19A1HTR1AGBA1 | |
| SCHEMBL8090880 | 0.67 | MCHR1 (0.32) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |