Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | TGM2 | P21980 | 5/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443535 | 0.80 | KMT2A (0.42) | ALDH1A1MEN1KMT2ATGM2EPHX2 | |
| SCHEMBL8090175 | 0.80 | MME (0.38) | — | |
| SCHEMBL8091477 | 0.78 | TBXA2R (0.40) | ALDH1A1EPHX2 | |
| SCHEMBL7439896 | 0.77 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AEPHX2POLB | |
| SCHEMBL8089916 | 0.76 | MMP8 (0.44) | EPHX2 | |
| SCHEMBL8083449 | 0.75 | EPHX2 (0.41) | EPHX2 | |
| SCHEMBL8083486 | 0.74 | EPHX2 (0.41) | EPHX2 | |
| SCHEMBL7443545 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AEPHX2POLB | |
| SCHEMBL8083551 | 0.73 | EPHX2 (0.41) | EPHX2 | |
| SCHEMBL8096021 | 0.73 | CYP1A2 (0.37) | ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |