Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083552 | 0.96 | CTSB (0.33) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL8095262 | 0.89 | HDAC3 (0.32) | CYP1A2TSHRNFKB1MAOBHDAC3 | |
| SCHEMBL8091664 | 0.84 | POLB (0.33) | — | |
| SCHEMBL8095242 | 0.83 | SPHK1 (0.32) | — | |
| SCHEMBL8095325 | 0.81 | POLB (0.33) | — | |
| SCHEMBL8091503 | 0.80 | SMYD3 (0.47) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL8083555 | 0.79 | NAMPT (0.46) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL8090161 | 0.73 | SPHK1 (0.33) | — | |
| SCHEMBL8083595 | 0.72 | CTSB (0.34) | — | |
| SCHEMBL8098109 | 0.71 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |