Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095325 | 0.97 | POLB (0.33) | POLBMAPTCA1CA2ALDH1A1 | |
| SCHEMBL8098109 | 0.87 | ALDH1A1 (0.33) | POLBALDH1A1LMNA | |
| SCHEMBL8095262 | 0.85 | HDAC3 (0.32) | SPHK2SPHK1 | |
| SCHEMBL8091620 | 0.85 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL8090129 | 0.85 | ALDH1A1 (0.34) | POLBALDH1A1SPHK2SPHK1 | |
| SCHEMBL8091498 | 0.84 | CYP1A2 (0.32) | — | |
| SCHEMBL8091597 | 0.83 | SPHK1 (0.34) | SPHK2SPHK1 | |
| SCHEMBL8090147 | 0.83 | SIGMAR1 (0.30) | — | |
| SCHEMBL8083552 | 0.81 | CTSB (0.33) | — | |
| SCHEMBL8091666 | 0.81 | NPC1 (0.47) | POLBCA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |