Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095271 | 0.85 | HSP90AA1 (0.44) | ALDH1A1HSP90AA1HSP90AB1KDM4EGAA | |
| SCHEMBL8091542 | 0.80 | KDM4E (0.39) | PDE6DALDH1A1LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL8091535 | 0.69 | HSP90AA1 (0.53) | ALDH1A1LMNAHSP90AA1HSP90AB1ACHE | |
| SCHEMBL24835214 | 0.68 | CYP4A11 (0.58) | ALDH1A1LMNACYP4A11CYP4F2ACHE | |
| SCHEMBL22897675 | 0.66 | SMN1; SMN2 (0.49) | ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL29559352 | 0.66 | SMN1; SMN2 (0.49) | ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL8090021 | 0.65 | PDK1 (0.53) | ALDH1A1HSP90AA1HSP90AB1GAAHPGD | |
| SCHEMBL7569237 | 0.65 | HTT (0.54) | ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL1794550 | 0.65 | CYP4A11 (0.61) | CYP4A11CYP4F2 | |
| SCHEMBL10661898 | 0.64 | CYP4A11 (0.69) | ALDH1A1CYP4A11CYP4F2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807628-B1 | Aromatic compound and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2000-12-20 | — | — | EP | disclosed |
| EP-0807628-A1 | Aromatic compound and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-11-19 | — | — | EP | disclosed |