Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.36 |
| ▸ | PDE6D | O43924 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091546 | 0.80 | PDE6D (0.42) | KDM4EHSP90AA1HSP90AB1PDE6DALDH1A1 | |
| SCHEMBL8095271 | 0.75 | HSP90AA1 (0.44) | KDM4EHSP90AA1HSP90AB1ALDH1A1GAA | |
| SCHEMBL8091535 | 0.68 | HSP90AA1 (0.53) | KMT2AHSP90AA1HSP90AB1ALDH1A1LMNA | |
| SCHEMBL24843670 | 0.66 | LOXL2 (0.53) | KDM4EKMT2AALDH1A1GAAMAPT | |
| SCHEMBL8090021 | 0.65 | PDK1 (0.53) | HSP90AA1HSP90AB1ALDH1A1GAAMAPT | |
| SCHEMBL24835214 | 0.62 | CYP4A11 (0.58) | KDM4EKMT2AALDH1A1LMNAGAA | |
| SCHEMBL7669610 | 0.62 | ALDH1A1 (0.61) | KMT2AHSP90AA1HSP90AB1ALDH1A1LMNA | |
| SCHEMBL7622296 | 0.62 | CYP4A11 (0.54) | KMT2ALNPEPERAP2POLBMAPT | |
| SCHEMBL29559352 | 0.61 | SMN1; SMN2 (0.49) | KDM4EKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL22897675 | 0.61 | SMN1; SMN2 (0.49) | KDM4EKMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807628-B1 | Aromatic compound and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2000-12-20 | — | — | EP | disclosed |
| EP-0807628-A1 | Aromatic compound and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-11-19 | — | — | EP | disclosed |