Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 4/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097409 | 0.74 | CYP19A1 (0.40) | CYP19A1MTNR1AMTNR1BFAAHADRA1D | |
| Fumaric Acid SCHEMBL8091873 | 0.73 | LMNA (0.41) | CYP19A1MTNR1AMTNR1BADRA1DADRA1A | |
| Fumaric Acid SCHEMBL8091860 | 0.73 | LMNA (0.41) | CYP19A1MTNR1AMTNR1BADRA1DADRA1A | |
| SCHEMBL6949244 | 0.70 | CYP19A1 (0.43) | CYP19A1ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6427473 | 0.61 | PREP (0.50) | CYP19A1MTNR1AMTNR1BADRA1DADRA1A | |
| SCHEMBL7304447 | 0.60 | DGAT1 (0.58) | CYP19A1MTNR1AMTNR1BPREPHTR1A | |
| SCHEMBL3406500 | 0.60 | DGAT1 (0.58) | CYP19A1MTNR1AMTNR1BPREPHTR1A | |
| SCHEMBL30612421 | 0.60 | DGAT1 (0.58) | CYP19A1MTNR1AMTNR1BPREPHTR1A | |
| SCHEMBL7292707 | 0.60 | DGAT1 (0.58) | CYP19A1MTNR1AMTNR1BPREPHTR1A | |
| SCHEMBL11790481 | 0.60 | MTNR1A (0.54) | MTNR1AMTNR1BFAAHNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |