Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PROC | P04070 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083888 | 0.87 | MMP8 (0.33) | KDM4EMTNR1AMTNR1BMMP8SPHK1 | |
| SCHEMBL8089916 | 0.82 | MMP8 (0.44) | MMP8SPHK1F2EPHX1 | |
| SCHEMBL8083449 | 0.81 | EPHX2 (0.41) | MMP8SPHK1F2PROC | |
| SCHEMBL8092142 | 0.80 | ALDH1A1 (0.48) | — | |
| SCHEMBL8096021 | 0.80 | CYP1A2 (0.37) | MAPTKDM4EMMP8SPHK1LMNA | |
| SCHEMBL8083486 | 0.80 | EPHX2 (0.41) | MMP8SPHK1F2PROCEPHX1 | |
| SCHEMBL8096623 | 0.78 | MC4R (0.39) | KDM4EF2 | |
| SCHEMBL8083551 | 0.78 | EPHX2 (0.41) | MMP8SPHK1F2PROC | |
| SCHEMBL8095058 | 0.76 | SPHK1 (0.43) | MMP8SPHK1F2PROC | |
| SCHEMBL8091477 | 0.76 | TBXA2R (0.40) | KDM4ELMNAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |