Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.37 |
| ▸ | ATR | Q13535 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | MTOR | P42345 | 4/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091635 | 0.86 | ATR (0.47) | PIK3CDATRPIK3CAMTORPDGFRB | |
| SCHEMBL8095575 | 0.86 | ALDH1A1 (0.49) | PIK3CDKDRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8097448 | 0.85 | PIK3CA (0.43) | PIK3CDATRPIK3CAMTORPIK3CG | |
| SCHEMBL8090195 | 0.84 | RAB9A (0.47) | PIK3CDATRPIK3CAMTORKDR | |
| SCHEMBL8083616 | 0.83 | ATR (0.42) | PIK3CDATRPIK3CAMTORMAPT | |
| SCHEMBL8089874 | 0.82 | PIK3CD (0.45) | PIK3CDATRPIK3CAMTORPIK3CG | |
| SCHEMBL8098188 | 0.82 | CA12 (0.44) | PIK3CDATRPIK3CAMTORMAPT | |
| SCHEMBL8097556 | 0.81 | PIK3CA (0.42) | PIK3CDATRPIK3CAMTORPIK3CG | |
| SCHEMBL8098293 | 0.81 | PIK3CA (0.42) | PIK3CDATRPIK3CAMTORPIK3CG | |
| SCHEMBL8095579 | 0.81 | PIK3CD (0.44) | PIK3CDATRPIK3CAMTORPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007748-A2 | TRISUBSTITUTED PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | WO | disclosed |