Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099967 | 0.88 | RAB9A (0.41) | RAB9APOLBNPC1MTORKMT2A | |
| SCHEMBL8095575 | 0.87 | ALDH1A1 (0.49) | RAB9ANPC1KMT2AMEN1PIK3CD | |
| SCHEMBL8084988 | 0.87 | RAB9A (0.41) | RAB9APOLBNPC1MTORKMT2A | |
| SCHEMBL8091838 | 0.86 | KMT2A (0.43) | RAB9APOLBNPC1MTORKMT2A | |
| SCHEMBL8091635 | 0.85 | ATR (0.47) | RAB9ANPC1MTORKMT2AMEN1 | |
| SCHEMBL8093540 | 0.85 | RAB9A (0.39) | RAB9APOLBNPC1MTORKMT2A | |
| SCHEMBL8097448 | 0.84 | PIK3CA (0.43) | MTORKMT2AMEN1PIK3CDATR | |
| SCHEMBL8092389 | 0.84 | PIK3CD (0.37) | RAB9ANPC1MTORKMT2APIK3CD | |
| SCHEMBL8083616 | 0.82 | ATR (0.42) | MTORKMT2AMEN1PIK3CDATR | |
| SCHEMBL8098188 | 0.82 | CA12 (0.44) | MTORKMT2AMEN1PIK3CDATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007748-A2 | TRISUBSTITUTED PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | WO | disclosed |