SCHEMBL8092584

SCHEMBL8092584

CCC(OC(=O)CC(C)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP3 P08254 1/20 0.41
MMP9 P14780 1/20 0.41
MMP13 P45452 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.35
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.33
KLK7 P49862 3/20 0.33
LAP3 P28838 2/20 0.32
MAPT P10636 1/20 0.31
ACE P12821 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17101672 0.86 MMP1 (0.57) MMP1MMP2MMP3MMP9MMP13
SCHEMBL1404146 0.81 KLK7 (0.38) MMP1MMP2MMP3MMP9MMP13
SCHEMBL28023347 0.79 SMN1; SMN2 (0.39) MMP1MMP2MMP3MMP9MMP13
SCHEMBL5907629 0.77 TSHR (0.39) MMP1MMP2MMP3MMP9MMP13
SCHEMBL9268142 0.77 MMP1 (0.45) MMP1MMP2MMP3MMP9MMP13
SCHEMBL27701925 0.75 TSHR (0.41) MMP1MMP2MMP3MMP9MMP13
SCHEMBL9065289 0.75 ALDH1A1 (0.46) SMN1; SMN2MAPTACE
SCHEMBL18668788 0.75 SMN1; SMN2 (0.37) MMP1MMP2MMP3MMP9MMP13
SCHEMBL9219486 0.74 CA1 (0.39) MMP1MMP2MMP3MMP9MMP13
SCHEMBL15945368 0.74 CYP1A2 (0.41) MMP1MMP2MMP3MMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP claimed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO claimed
EP-4595775-A2 BHB-CITRATE COMBINATION PRODUCTS FOR RENAL HEALTH AND TREATING DISEASE The Regents of the University of California (US) 2025-08-06 EP disclosed
US-20240000735-A1 Compositions and Methods for Dietary Management THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-04 US disclosed
WO-2022173813-A1 IMPROVED BHB-CITRATE FORMULATIONS FOR PROMOTING HEALTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-18 WO disclosed
CN-114144174-A Methods and compositions for supporting kidney health 加利福尼亚大学董事会 2022-03-04 CN disclosed
EP-3937920-A1 METHODS AND COMPOSITIONS FOR SUPPORTING RENAL HEALTH The Regents of the University of California (US) 2022-01-19 EP disclosed
US-20210244694-A1 BHB-Citrate Combination Products for Renal Health and Treating Disease THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-08-12 US disclosed
US-20210244695-A1 Methods and Compositions for Supporting Renal Health THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-08-12 US disclosed
US-11013705-B2 Methods and compositions for supporting renal health THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-05-25 US disclosed
US-20200289444-A1 Methods and Compositions for Supporting Renal Health THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-09-17 US disclosed
WO-2020186154-A1 METHODS AND COMPOSITIONS FOR SUPPORTING RENAL HEALTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-09-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200289444-A1 Methods and Compositions for Supporting Renal Health PKD2, GPR119, PKD1 MMP1 4010/4885MMP2 4784/4885MMP3 3721/4885
US-20240000735-A1 Compositions and Methods for Dietary Management PKD2, PKD1, GPR39 MMP1 4165/4885MMP2 4857/4885MMP3 4434/4885
US-11013705-B2 Methods and compositions for supporting renal health PKD2, GPR119, PKD1 MMP1 4010/4885MMP2 4784/4885MMP3 3721/4885
US-20210244694-A1 BHB-Citrate Combination Products for Renal Health and Treating Disease PKD2, PKD1, GPR119 MMP1 4351/4885MMP2 4838/4885MMP3 4349/4885
US-20210244695-A1 Methods and Compositions for Supporting Renal Health PKD2, GPR119, PKD1 MMP1 4010/4885MMP2 4784/4885MMP3 3721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.