Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809379 | 0.85 | ELANE (0.58) | ELANEKMT2AGAALMNANPC1 | |
| SCHEMBL539733 | 0.84 | LMNA (0.59) | ELANEMEN1KMT2AHTTCES2 | |
| SCHEMBL1167621 | 0.84 | KMT2A (0.58) | MEN1KMT2AHTTCES2CES1 | |
| SCHEMBL809353 | 0.82 | ELANE (0.52) | ELANEMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL24250565 | 0.82 | ELANE (0.73) | ELANEMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL31621467 | 0.79 | ACHE (0.50) | ELANEMEN1KMT2AHTTLMNA | |
| SCHEMBL9875360 | 0.79 | OGG1 (0.54) | ELANEKMT2AHTTLMNACYP3A4 | |
| SCHEMBL26564348 | 0.79 | LMNA (0.61) | ELANEMEN1KMT2AHTTLMNA | |
| SCHEMBL16300529 | 0.79 | ELANE (0.59) | ELANEMEN1KMT2AESR1ESR2 | |
| SCHEMBL28567642 | 0.78 | ELANE (0.44) | ELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802726-B1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | ADVANCED POLYMERIK PTY LTD (AU) | 2011-11-30 | — | — | EP | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| EP-1802726-A4 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | POLYMERS AUSTRALIA PTY LTD (AU) | 2008-04-30 | — | — | EP | disclosed |
| EP-1802726-A1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | Polymers Australia PTY Limited (AU) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006024099-A1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2006-03-09 | — | — | WO | disclosed |