Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809187 | 0.82 | ELANE (0.53) | ELANEALOX15CA2KMT2AMEN1 | |
| SCHEMBL809319 | 0.82 | ELANE (0.53) | ELANEKMT2AMEN1LMNATP53 | |
| SCHEMBL392901 | 0.82 | LMNA (0.47) | ELANEKMT2AMEN1KDM4ELMNA | |
| SCHEMBL195019 | 0.78 | LMNA (0.43) | ELANEKMT2AMEN1KDM4ELMNA | |
| SCHEMBL11699992 | 0.77 | MEN1 (0.32) | GLRA1KMT2AMEN1 | |
| SCHEMBL28312881 | 0.76 | ELANE (0.50) | ELANEALOX15CA2HTR1DHTR1B | |
| SCHEMBL1814578 | 0.76 | KMT2A (0.47) | GLRA1KMT2AMEN1 | |
| SCHEMBL19480254 | 0.75 | ELANE (0.46) | ELANEALOX15CA2KMT2AMEN1 | |
| SCHEMBL16675175 | 0.74 | ELANE (0.68) | ELANEKMT2AMEN1LMNAMAPT | |
| SCHEMBL13259257 | 0.74 | LMNA (0.41) | ELANEKMT2AMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802726-B1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | ADVANCED POLYMERIK PTY LTD (AU) | 2011-11-30 | — | — | EP | disclosed |
| EP-1802726-B1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | ADVANCED POLYMERIK PTY LTD (AU) | 2011-11-30 | — | — | EP | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| EP-1802726-A4 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | POLYMERS AUSTRALIA PTY LTD (AU) | 2008-04-30 | — | — | EP | disclosed |
| EP-1802726-A1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | Polymers Australia PTY Limited (AU) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006024099-A1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2006-03-09 | — | — | WO | disclosed |