Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405727 | 0.77 | BRD4 (0.38) | MAPTALDH1A1MEN1KMT2AHDAC2 | |
| SCHEMBL8405648 | 0.73 | ALDH1A1 (0.33) | MAPTLMNAKIF11TSHRALDH1A1 | |
| SCHEMBL8519231 | 0.72 | GAA (0.37) | MAPTLMNAALDH1A1HPGD | |
| SCHEMBL8406820 | 0.72 | KMT2A (0.39) | MAPTLMNACYP3A4ALDH1A1MEN1 | |
| SCHEMBL8816172 | 0.71 | KIF11 (0.35) | MAPTLMNAKIF11ALDH1A1MEN1 | |
| SCHEMBL8812237 | 0.70 | CCKAR (0.40) | MAPTKIF11ALDH1A1KMT2A | |
| SCHEMBL8406772 | 0.69 | POLB (0.33) | ALDH1A1 | |
| SCHEMBL8814705 | 0.67 | CCKAR (0.49) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8813766 | 0.66 | CCKAR (0.39) | — | |
| SCHEMBL8797930 | 0.66 | HDAC3 (0.51) | SCN9AHDAC3HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096885-A | EXHIBIT AGONIST ACTIVITY FOR CCK-A RECEPTORS THEREBY ENABLING THEM TO MODULATE THE HORMONES GASTRIN AND CHOLECYSTOKININ IN MAMMALS. | GLAXO WELLCOME INC. (US) | 2000-08-01 | — | — | US | disclosed |