Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 3/20 | 0.49 |
| ▸ | CCKBR | P32239 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808190 | 0.81 | MAPT (0.43) | CCKARCCKBRGAAMAPTALDH1A1 | |
| SCHEMBL8813766 | 0.81 | CCKAR (0.39) | CCKARCCKBR | |
| SCHEMBL8816172 | 0.77 | KIF11 (0.35) | CCKARCCKBRMAPTPOLBALDH1A1 | |
| SCHEMBL8812237 | 0.75 | CCKAR (0.40) | CCKARCCKBRMAPTPOLBALDH1A1 | |
| SCHEMBL8519231 | 0.74 | GAA (0.37) | CCKARCCKBRTP53GAAMAPT | |
| SCHEMBL8804640 | 0.74 | CCKAR (0.85) | CCKARCCKBR | |
| SCHEMBL7753002 | 0.73 | CCKBR (0.37) | CCKARCCKBRGAAMAPTALDH1A1 | |
| SCHEMBL8401920 | 0.72 | CCKBR (0.47) | CCKARCCKBR | |
| SCHEMBL8405648 | 0.71 | ALDH1A1 (0.33) | CCKARCCKBRGAAMAPTALDH1A1 | |
| SCHEMBL8797040 | 0.68 | NOTCH1 (0.45) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755384-A1 | CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES | GLAXO WELLCOME INC. (US) | 1997-01-29 | — | — | EP | claimed |
| WO-1995028391-A1 | CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES | GLAXO WELLCOME INC. (US) | 1995-10-26 | — | — | WO | claimed |