Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 5/20 | 0.31 |
| ▸ | RAB9A | P51151 | 5/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406820 | 0.91 | KMT2A (0.39) | ALDH1A1KDM4EKMT2AALOX15HSD17B10 | |
| SCHEMBL8519231 | 0.86 | GAA (0.37) | ALDH1A1CCKARCCKBRRAB9AHPGD | |
| SCHEMBL8406772 | 0.83 | POLB (0.33) | ALDH1A1CCKARCCKBR | |
| SCHEMBL8405727 | 0.78 | BRD4 (0.38) | ALDH1A1KDM4EKMT2AHSD17B10CCKBR | |
| SCHEMBL7753002 | 0.78 | CCKBR (0.37) | ALDH1A1KMT2ACCKARCCKBRRAB9A | |
| SCHEMBL8816172 | 0.74 | KIF11 (0.35) | ALDH1A1KMT2ACCKARCCKBRHPGD | |
| SCHEMBL8093418 | 0.73 | MAPT (0.35) | ALDH1A1KMT2AHPGDLMNATSHR | |
| SCHEMBL8814705 | 0.71 | CCKAR (0.49) | ALDH1A1KMT2ACCKARCCKBRPKM | |
| SCHEMBL8402034 | 0.71 | CCKAR (0.57) | CCKARCCKBR | |
| SCHEMBL8813766 | 0.71 | CCKAR (0.39) | CCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756602-B1 | CCK OR GASTRIN MODULATING 5-HETEROCYCLIC-1,5-BENZODIAZEPINES | GLAXO WELLCOME INC (US) | 1999-06-30 | — | — | EP | disclosed |