Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405648 | 0.86 | ALDH1A1 (0.33) | GAAMAPTALDH1A1LMNARAB9A | |
| SCHEMBL8406820 | 0.84 | KMT2A (0.39) | MAPTALDH1A1LMNANPSR1RAB9A | |
| SCHEMBL7753002 | 0.81 | CCKBR (0.37) | GAAMAPTALDH1A1RAB9ACCKAR | |
| SCHEMBL8401920 | 0.80 | CCKBR (0.47) | CCKARCCKBR | |
| SCHEMBL8406772 | 0.80 | POLB (0.33) | ALDH1A1CCKARCCKBRPOLB | |
| SCHEMBL8406839 | 0.77 | CCKAR (0.44) | GAAMAPTALDH1A1CCKARCCKBR | |
| SCHEMBL8405727 | 0.75 | BRD4 (0.38) | MAPTTP53ALDH1A1HPGDTDP1 | |
| SCHEMBL8816172 | 0.75 | KIF11 (0.35) | MAPTALDH1A1LMNAHPGDCCKAR | |
| SCHEMBL8803972 | 0.74 | CCKAR (0.39) | MAPTALDH1A1LMNARAB9ACCKAR | |
| SCHEMBL8814705 | 0.74 | CCKAR (0.49) | GAAMAPTTP53ALDH1A1CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756602-B1 | CCK OR GASTRIN MODULATING 5-HETEROCYCLIC-1,5-BENZODIAZEPINES | GLAXO WELLCOME INC (US) | 1999-06-30 | — | — | EP | disclosed |