Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 10/20 | 0.44 |
| ▸ | CA1 | P00915 | 9/20 | 0.44 |
| ▸ | CA2 | P00918 | 9/20 | 0.44 |
| ▸ | CA12 | O43570 | 8/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099443 | 0.91 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8093715 | 0.85 | CNR1 (0.46) | CA9CA1CA2CA12PTGS2 | |
| SCHEMBL8094849 | 0.84 | HPGD (0.48) | CA9CA1CA2CA12PTGS2 | |
| SCHEMBL8092670 | 0.83 | GLA (0.44) | CA9CA1CA2CA12PTGS2 | |
| SCHEMBL8093490 | 0.83 | ALDH1A1 (0.51) | CA9CA1CA2CA12CA4 | |
| SCHEMBL8092536 | 0.82 | PTGS2 (0.43) | CA9CA1CA2CA12PTGS2 | |
| SCHEMBL8421223 | 0.81 | NPSR1 (0.41) | — | |
| SCHEMBL8086911 | 0.81 | HPGD (0.45) | CA9CA1CA2CA12PTGS2 | |
| SCHEMBL8093987 | 0.80 | PTGS2 (0.48) | CA9CA1CA2CA12PTGS2 | |
| SCHEMBL8094187 | 0.79 | CNR1 (0.50) | CA9CA1CA2CA12PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-B1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-12-27 | — | — | EP | disclosed |