Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094729 | 0.92 | PTGS2 (0.49) | GLAPTGS2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8776744 | 0.86 | SQOR (0.46) | GLACHRNA7PTGS2KDM4EL3MBTL1 | |
| SCHEMBL8095872 | 0.83 | ALDH1A1 (0.55) | PTGS2KDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL8093864 | 0.83 | CA9 (0.44) | CHRNA7PTGS2CA1CA2CA9 | |
| SCHEMBL8086911 | 0.82 | HPGD (0.45) | PTGS2KDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL8094551 | 0.80 | CNR1 (0.49) | PTGS2L3MBTL1NPSR1CA1CA2 | |
| SCHEMBL8093983 | 0.80 | CNR1 (0.44) | CHRNA7PTGS2KDM4EL3MBTL1CA1 | |
| SCHEMBL8421064 | 0.79 | ALDH1A1 (0.49) | GLAKDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL8093987 | 0.79 | PTGS2 (0.48) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL8094187 | 0.78 | CNR1 (0.50) | PTGS2CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-B1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-12-27 | — | — | EP | disclosed |