Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099386 | 0.93 | HTR2A (0.42) | DHFRSLC6A2SLC6A4SLC6A3CNR2 | |
| SCHEMBL8093886 | 0.86 | TAAR1 (0.40) | SLC6A2SLC6A4SLC6A3TYMPCNR2 | |
| SCHEMBL8101895 | 0.84 | TAAR1 (0.43) | SLC6A2SLC6A4SLC6A3TYMPCNR2 | |
| SCHEMBL8095786 | 0.84 | LTA4H (0.46) | SLC6A2SLC6A4SLC6A3LTA4HTAAR1 | |
| SCHEMBL6548002 | 0.84 | TAAR1 (0.46) | TYMPSHBGCNR2GPR55CNR1 | |
| SCHEMBL11210876 | 0.84 | TAAR1 (0.46) | TYMPSHBGCNR2GPR55CNR1 | |
| SCHEMBL8100912 | 0.83 | CNR1 (0.43) | SLC6A2SLC6A4SLC6A3CNR2GPR55 | |
| SCHEMBL8096090 | 0.82 | CNR2 (0.48) | CNR2GPR55CNR1TAAR1 | |
| SCHEMBL8094436 | 0.81 | LMNA (0.50) | DHFRLTA4H | |
| SCHEMBL8100945 | 0.80 | CNR2 (0.47) | CNR2GPR55CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |