Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.36 |
| ▸ | CDK4 | P11802 | 3/20 | 0.36 |
| ▸ | CCND1 | P24385 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080577 | 0.86 | CDK4 (0.36) | GSK3BCDK4CCND1ALDH1A1NPSR1 | |
| SCHEMBL7430843 | 0.73 | GPR84 (0.41) | GSK3BCDK4CCND1ALDH1A1NPSR1 | |
| SCHEMBL8853276 | 0.72 | CDK4 (0.40) | GSK3BCDK4CCND1ALDH1A1NPSR1 | |
| SCHEMBL11466604 | 0.71 | ALDH1A1 (0.56) | PTPN1ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL28324766 | 0.71 | ALDH1A1 (0.44) | PTPN1ALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL1029435 | 0.70 | ALDH1A1 (0.42) | GSK3BCDK4CCND1ALDH1A1NPSR1 | |
| SCHEMBL3852137 | 0.70 | CDK4 (0.44) | GSK3BCDK4CCND1ALDH1A1NPSR1 | |
| SCHEMBL1756365 | 0.70 | TRPM4 (0.48) | GSK3BCDK4CCND1MAPTGSK3A | |
| SCHEMBL9556428 | 0.69 | CDK4 (0.39) | GSK3BCDK4CCND1MAPTGPR84 | |
| SCHEMBL789452 | 0.68 | TRPM4 (0.47) | GSK3BCDK4CCND1MAPTGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160128-A | Tritioacetylating reagents and processes for preparation thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-12-12 | — | — | US | disclosed |