SCHEMBL8094299

SCHEMBL8094299

CC(Cl)c1cccc(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.45
ACP3 P15309 1/20 0.44
AOC3 Q16853 1/20 0.43
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
OPRM1 P35372 1/20 0.41
OPRD1 P41143 1/20 0.41
OPRK1 P41145 1/20 0.41
OPRL1 P41146 1/20 0.41
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
ADRA1D P25100 1/20 0.40
SLC2A1 P11166 1/20 0.40
HPGD P15428 1/20 0.39
PDE1B Q01064 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30549338 1.00 PNMT (0.45) PNMTACP3AOC3ALDH1A1TSHR
SCHEMBL8897762 0.85 PGK1 (0.44) ALDH1A1TSHRADRB1HPGD
SCHEMBL1047528 0.84 ACP3 (0.47) PNMTACP3AOC3ALDH1A1TSHR
SCHEMBL29428797 0.83 PGR (0.47) PNMTACP3AOC3ALDH1A1TSHR
SCHEMBL254476 0.83 PGR (0.47) PNMTACP3AOC3ALDH1A1TSHR
SCHEMBL2601111 0.83 PNMT (0.47) PNMTACP3AOC3ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL16197665 0.81 PGR (0.46) PNMTACP3AOC3ALDH1A1TSHR
SCHEMBL29712699 0.80 ACP3 (0.47) PNMTACP3AOC3ALDH1A1TSHR
SCHEMBL5318844 0.80 TSHR (0.50) PNMTACP3AOC3ALDH1A1TSHR
SCHEMBL11614094 0.80 ACP3 (0.47) PNMTACP3AOC3ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059820-A Method for synthesizing carboxylic acid compound by titanium catalysis 陕西师范大学 2026-05-19 CN disclosed
CN-113582818-B Synthesis method of 3-halogen-2-alkylphenol 上海日异生物科技有限公司 2023-08-01 CN disclosed
CN-113582818-A Synthetic method of 3-halogen-2-alkylphenol 上海日异生物科技有限公司 2021-11-02 CN disclosed
EP-1053990-A2 A method of producing an aromatic ketone and an aromatic ketone composition containing it TORAY INDUSTRIES, INC. (JP) 2000-11-22 EP disclosed
US-4081596-A DIURETIC, SALURETIC, ANTIHYPERTENSIVE, ANTITHROMBOTIC BAYER AKTIENGESELLSCHAFT (DT) 1978-03-28 US disclosed
US-4005215-A DIURETIC BAYER AKTIENGESELLSCHAFT (DT) 1977-01-25 US disclosed
US-3978077-A DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC BAYER AKTIENGESELLSCHAFT (GB) 1976-08-31 US disclosed
US-3957814-A DIURETICS, SALURETICS, HYPOTENSIVE AGENTS, ANTITHROMBOTIC BAYER AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed