Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.57 |
| ▸ | MMP3 | P08254 | 4/20 | 0.57 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12195056 | 0.87 | CTSD (0.53) | CTSLCTSSCTSDCTSBCTSK | |
| SCHEMBL10257423 | 0.87 | CTSD (0.53) | CTSLCTSSCTSDCTSBCTSK | |
| SCHEMBL8649599 | 0.85 | MMP2 (0.54) | MMP2MMP3CTSLCTSSCTSD | |
| SCHEMBL8280590 | 0.85 | MMP2 (0.54) | MMP2MMP3CTSLCTSSCTSD | |
| SCHEMBL478316 | 0.84 | SYK (0.54) | CTSLCTSSCTSDCTSBCTSK | |
| SCHEMBL738204 | 0.84 | SYK (0.54) | CTSLCTSSCTSDCTSBCTSK | |
| SCHEMBL13798764 | 0.83 | CTSK (0.52) | CTSLCTSSCTSDCTSBCTSK | |
| SCHEMBL16328282 | 0.82 | ALDH1A1 (0.54) | CTSLCTSSCTSDCTSBCTSK | |
| SCHEMBL8667196 | 0.82 | TRPM8 (0.54) | CTSLCTSSCTSBCTSKSYK | |
| SCHEMBL3527938 | 0.82 | CTSD (0.54) | CTSLCTSSCTSDCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821666-B1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2000-12-27 | — | — | EP | disclosed |