Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088578 | 0.91 | EPHX2 (0.40) | EPHX2HRH3AR | |
| SCHEMBL8088615 | 0.89 | EPHX2 (0.36) | EPHX2HRH3AR | |
| SCHEMBL8081388 | 0.88 | EPHX2 (0.40) | EPHX2HRH3 | |
| SCHEMBL7342953 | 0.87 | OXTR (0.36) | EPHX2UTS2R | |
| SCHEMBL8089444 | 0.83 | AR (0.46) | AR | |
| SCHEMBL8094956 | 0.83 | LIPG (0.38) | EPHX2HRH3NEK2 | |
| SCHEMBL7335906 | 0.79 | OXTR (0.37) | EPHX2 | |
| SCHEMBL7333661 | 0.78 | OXTR (0.42) | — | |
| SCHEMBL7342824 | 0.77 | OXTR (0.40) | EPHX2 | |
| SCHEMBL9013863 | 0.77 | GPR119 (0.38) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |