Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 6/20 | 0.39 |
| ▸ | MC3R | P41968 | 6/20 | 0.39 |
| ▸ | MC1R | Q01726 | 5/20 | 0.39 |
| ▸ | MC5R | P33032 | 5/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096021 | 0.91 | CYP1A2 (0.37) | MC4RMC3RMC1RTPSAB1HDAC1 | |
| SCHEMBL8083449 | 0.89 | EPHX2 (0.41) | TPSAB1ERCC1ERCC4F2 | |
| SCHEMBL8083486 | 0.88 | EPHX2 (0.41) | TPSAB1ERCC1ERCC4F2 | |
| SCHEMBL8083551 | 0.87 | EPHX2 (0.41) | TPSAB1F2 | |
| SCHEMBL8095058 | 0.85 | SPHK1 (0.43) | TPSAB1F2 | |
| SCHEMBL8089916 | 0.82 | MMP8 (0.44) | F2 | |
| SCHEMBL8090175 | 0.78 | MME (0.38) | F2KDM4E | |
| SCHEMBL8083888 | 0.78 | MMP8 (0.33) | F2KDM4E | |
| SCHEMBL8091412 | 0.77 | ALDH1A1 (0.34) | F2 | |
| SCHEMBL8083456 | 0.77 | MMP8 (0.46) | TPSAB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |