Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095236 | 0.87 | RIPK1 (0.52) | RIPK1EPHX2POLBMMP8ALDH1A1 | |
| SCHEMBL8098099 | 0.87 | RIPK1 (0.44) | RIPK1EPHX2POLBMMP8FAAH | |
| SCHEMBL10937862 | 0.77 | RIPK1 (0.64) | RIPK1EPHX2MMP8ALDH1A1MAPT | |
| SCHEMBL8098103 | 0.75 | RIPK1 (0.51) | RIPK1EPHX2POLBMMP8OPRK1 | |
| SCHEMBL8083527 | 0.75 | RIPK1 (0.40) | RIPK1EPHX2POLBMMP8ALDH1A1 | |
| SCHEMBL8095058 | 0.75 | SPHK1 (0.43) | EPHX2MMP8 | |
| SCHEMBL8083449 | 0.73 | EPHX2 (0.41) | EPHX2MMP8 | |
| SCHEMBL8083551 | 0.73 | EPHX2 (0.41) | EPHX2MMP8 | |
| SCHEMBL8083486 | 0.72 | EPHX2 (0.41) | EPHX2MMP8 | |
| SCHEMBL7432257 | 0.72 | F2 (0.40) | RIPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |