Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | PPID | Q08752 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095253 | 0.89 | RIPK1 (0.39) | RIPK1L3MBTL1MAPTMMP8CTSK | |
| SCHEMBL8091386 | 0.87 | RIPK1 (0.43) | RIPK1L3MBTL1MAPTMMP8CTSK | |
| SCHEMBL8095236 | 0.81 | RIPK1 (0.52) | RIPK1MAPTMMP8OPRK1TLR2 | |
| SCHEMBL8095454 | 0.78 | MMP8 (0.37) | L3MBTL1MAPTMMP8TPSAB1EPHX2 | |
| SCHEMBL8095158 | 0.77 | MMP8 (0.36) | L3MBTL1MAPTMMP8TPSAB1EPHX2 | |
| SCHEMBL8091532 | 0.77 | MMP8 (0.36) | L3MBTL1MAPTMMP8TPSAB1EPHX2 | |
| SCHEMBL7432264 | 0.76 | F2 (0.36) | RIPK1L3MBTL1MAPTCTSKOPRK1 | |
| SCHEMBL8091531 | 0.76 | MMP8 (0.35) | L3MBTL1MAPTMMP8TPSAB1EPHX2 | |
| SCHEMBL7432257 | 0.76 | F2 (0.40) | RIPK1TLR2POLB | |
| SCHEMBL8095232 | 0.75 | RIPK1 (0.45) | RIPK1MAPTMMP8OPRK1PPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |