Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095232 | 0.87 | RIPK1 (0.45) | RIPK1POLBEPHX2MMP8ALDH1A1 | |
| SCHEMBL8098103 | 0.87 | RIPK1 (0.51) | RIPK1POLBEPHX2MMP8OPRK1 | |
| SCHEMBL8083527 | 0.81 | RIPK1 (0.40) | RIPK1POLBEPHX2MMP8ALDH1A1 | |
| SCHEMBL10937862 | 0.81 | RIPK1 (0.64) | RIPK1EPHX2MMP8ALDH1A1MAPT | |
| SCHEMBL7432257 | 0.80 | F2 (0.40) | RIPK1POLBKMT2ATLR2 | |
| SCHEMBL7438658 | 0.77 | RIPK1 (0.68) | RIPK1EPHX2MMP8ALDH1A1MAPT | |
| SCHEMBL7432264 | 0.77 | F2 (0.36) | RIPK1POLBMAPTOPRK1KMT2A | |
| SCHEMBL24486730 | 0.76 | EPHX2 (0.67) | EPHX2SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL8098099 | 0.75 | RIPK1 (0.44) | RIPK1POLBEPHX2MMP8OPRK1 | |
| Acetic Acid SCHEMBL28068598 | 0.74 | CYP2C9 (0.53) | RIPK1ALDH1A1MAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |