Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30610782 | 1.00 | PKM (0.57) | PKMGAACA5AHTTTDP1 | |
| SCHEMBL8095827 | 0.88 | GAA (0.65) | PKMGAACA5AHTTTDP1 | |
| SCHEMBL9633026 | 0.85 | PKM (0.55) | PKMCA5AHTTTDP1TSHR | |
| SCHEMBL9632900 | 0.85 | CA12 (0.48) | PKMHTTTDP1ALDH1A1ADRA1D | |
| SCHEMBL30997420 | 0.85 | CA5A (0.47) | PKMGAACA5AHTTTDP1 | |
| SCHEMBL4660848 | 0.85 | CA5A (0.47) | PKMGAACA5AHTTTDP1 | |
| SCHEMBL3945648 | 0.84 | PKM (0.50) | PKMGAACA5AHTTTDP1 | |
| SCHEMBL3951669 | 0.84 | PKM (0.50) | PKMGAACA5AHTTTDP1 | |
| SCHEMBL6550393 | 0.84 | PKM (0.54) | PKMGAACA5AHTTTDP1 | |
| SCHEMBL9633753 | 0.83 | ADRA1D (0.41) | PKMGAAHTTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111876449-B | Preparation method of R- (-) -5- (2-aminopropyl) -2-methoxybenzenesulphonamide | 苏利制药科技江阴有限公司 | 2022-02-08 | — | — | CN | claimed |
| CN-111876449-A | Preparation method of R- (-) -5- (2-aminopropyl) -2-methoxybenzenesulphonamide | 江苏苏利精细化工股份有限公司 | 2020-11-03 | — | — | CN | claimed |
| CN-111320559-A | Preparation method of tamsulosin hydrochloride | 苏州盛迪亚生物医药有限公司 | 2020-06-23 | — | — | CN | claimed |
| EP-1603866-B1 | A PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE (R) OR (S)-5-(2-AMINOPROPYL)-2-METHOXYBENZENESULFONAMIDE | CADILA HEALTHCARE LTD (IN) | 2009-04-29 | — | — | EP | claimed |
| EP-1539684-B1 | BENZENESULPHONAMIDES AND PROCESS FOR THEIR PREPARATION | RICHTER GEDEON NYRT (HU) | 2009-04-15 | — | — | EP | claimed |
| US-20060173214-A1 | Process for the preparation of enantiomerically pure (r) or (s)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide | CADILA HEALTHCARE LIMITED (IN) | 2006-08-03 | — | — | US | claimed |
| EP-1603866-A1 | A PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE (R) OR (S)-5-(2-AMINOPROPYL)-2-METHOXYBENZENESULFONAMIDE | CADILA HEALTHCARE LTD. (IN) | 2005-12-14 | — | — | EP | claimed |
| EP-1539684-A1 | BENZENESULPHONAMIDES AND PROCESS FOR THEIR PREPARATION | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2005-06-15 | — | — | EP | claimed |
| EP-1444199-A1 | RACEMIC TAMSULOSIN FREE BASE AND METHODS OF MAKING THE SAME | Synthon B.V. (NL) | 2004-08-11 | — | — | EP | claimed |
| WO-2004058694-A1 | A PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE (R) OR (S)-5-(2-AMINOPROPYL)-2-METHOXYBENZENESULFONAMIDE | CADILA HEALTHCARE LIMITED (IN) | 2004-07-15 | — | — | WO | claimed |
| WO-2004022532-A1 | BENZENESULPHONAMIDES AND PROCESS FOR THEIR PREPARATION | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2004-03-18 | — | — | WO | claimed |
| US-20030109752-A1 | Process for resolution of tamsulosin and compounds, compositons, and processes associated therewith | SYNTHON IP INC. | 2003-06-12 | — | — | US | claimed |
| WO-2003037851-A1 | RACEMIC TAMSULOSIN FREE BASE AND METHODS OF MAKING THE SAME | SYNTHON B.V. (NL) | 2003-05-08 | — | — | WO | claimed |
| EP-4229045-B1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | BROAD INST INC (US) | 2025-11-12 | — | — | EP | disclosed |
| US-12357603-B2 | Acyl sulfonamides for treating cancer | BAYER AKTIENGESELLSCHAFT (DE) | 2025-07-15 | — | — | US | disclosed |
| CN-119019296-A | Method for preparing tamsulosin or pharmaceutically acceptable salt thereof by using immobilized catalyst | 江苏恒瑞医药股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| US-4971990-A | HYPOTENSIVE AGENTS, DYSUREA | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0380144-A1 | Process for producing optically active benzene-sulfonamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1990-08-01 | — | — | EP | disclosed |
| EP-0331943-A1 | Phenoxyethylamine derivatives, process for preparing the same, and composition for exhibiting excellent alpha-1-blocking activity containing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0257787-A1 | Process for producing optically active benzene-sulfonamide derivates | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109752-A1 | Process for resolution of tamsulosin and compounds, compositons, and processes associated therewith | NPSR1, REN, PTMA | PKM 757/4885GAA 2662/4885CA5A 2226/4885 |
| US-12357603-B2 | Acyl sulfonamides for treating cancer | KAT6A, KAT6B, KAT2A | PKM 2459/4885GAA 1486/4885CA5A 1163/4885 |
| US-20060173214-A1 | Process for the preparation of enantiomerically pure (r) or (s)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide | SRMS, SPR, SRR | PKM 3229/4885GAA 2504/4885CA5A 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.